Endocrine Abstracts

Introduction: Polycystic ovary syndrome (PCOS) is one of the most commonly diagnosed endocrinopathies in women of reproductive age and is associated with an increasing number of metabolic comorbidities. About 50% of PCOS patients are obese, while insulin resistance affect up to 70% of these women. The endocannabinoid system contributes to human energy homeostasis. CNR1 is a biological candidate for human obesity and related metabolic disorders.Aims: The ...

Pleiotropic effects of vit. D in the etiology of obesity, metabolic syndrome and diabetes are still debated. So far published reports considered only changes in vit D plasma level in individuals with obesity and diabetes, and did not take into account the role of polymorphisms in the vit. D receptor gene.The aim of the study was to evaluate obesity, carbohydrate and lipid metabolism and vitamin D level in two VDR polymorphisms (Fok and Bsm) in Polish agi...

The levels of bone turnover markers are elevated e.g. in osteoporosis, neoplastic diseases with bone involvement (e.g. myeloma). Recently bone markers have been found to play an important role in other diseases, like cardiovascular diseases (CVD). Vitamin D, which plays a role in body metabolism, is also an important hormone maintaining bone homeostasis.The aim of the study was to evaluate the levels of bone turnover markers (osteoprotegerin and ICTP) in...